Lupus patients in England in remission after pioneering NHS trial of GM therapy

Five lupus patients in England achieved remission using CAR T-cell therapy, which genetically modifies their own immune cells. This breakthrough treatment could offer a potential cure for the chronic autoimmune disease.

Lupus and similar autoimmune diseases significantly impact quality of life. Success with this therapy could offer hope to millions of autoimmune disease patients worldwide.

Doctors say therapy that genetically modifies person’s T-cells could offer cure for chronic autoimmune disease Five lupus patients in England are in remission after being treated with a revolutionary therapy that genetically modifies their own cells, in a medical breakthrough that could offer people a cure, doctors have said. CAR (chimeric antigen receptor) T-cell therapy involves removing a type of white blood cell also called T lymphocytes, which are crucial for hunting out infected or damaged cells, and engineering them to spot and destroy disease. The T-cells are then fed back into the patient via an infusion to reset their immune system. Continue reading...